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High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: that Box 6/Box 7-containing FAKi> variants (FAKi>6/7i>sup>) were observed in 7that FAKi>6/7i>sup> was positive in 14 (93.3%) of 15 BrNECs but 0FAKi>6/7i>sup>-positive pancreatic tumors and breast tumors, which promoted the formationof FAKi>6/7i>sup> in cells.These results suggested that FAKi>6/7i>sup> could be a biomarker of NENs and represent

Keywords： FAKi>6/7i>sup> SRRM4 neuroendocrine neoplasms pancreas breast

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K+sup> and Na+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2, Pages 144-149 doi: 10.15302/J-FASE-2014016

Abstract: Maintenance of ion homeostasis, particularly the regulation of K and Na uptake, is important for all plants to adapt to salinity. Observations on ionic response to salinity and net fluxes of K , Na in the root exhibited by plants during salt stress have highlighted the need for further investigation. The objectives of this study were to compare salt adaptation of two Chinese Iris ( Pall. var. (Fisch.) Koidz.) populations, and to improve understanding of adaptation to salinity exhibited by plants. Plants used in this study were grown from seeds collected in the Xinjiang Uygur Autonomous Region (Xj) and Beijing Municipality (Bj), China. Hydroponically-grown seedlings of the two populations were supplied with nutrient solutions containing 0.1 (control) and 140 mmol·L NaCl. After 12 days, plants were harvested for determination of relative growth rate and K , Na concentrations. Net fluxes of K , Na from the apex and along the root axis to 10.8 mm were measured using non-invasive micro-test technique. With 140 mmol·L NaCl treatment, shoots for population Xj had larger relative growth rate and higher K concentration than shoots for population Bj. However, the Na concentrations in both shoots and roots were lower for Xj than those for Bj. There was a lower net efflux of K found in population Xj than by Bj in the mature zone (approximately 2.4-10.8 mm from root tip). However, no difference in the efflux of Na between the populations was obtained. Population Xj of continued to grow normally under NaCl stress, and maintained a higher K /Na ratio in the shoots. These traits, which were associated with lower K leakage, help population Xj adapt to saline environments.

Keywords： Iris lacteai> Pall. var. chinensisi> (Fisch.)Koidz population K+sup> and Na+sup> ion flux non-invasive micro-test technique

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Therapeutic Characterization of 131sup>I-Labeled Humanized Anti-B7-H3 Antibodies for Radioimmunotherapy Article

Fengqing Fu, Meng Zheng, Shandong Zhao, Yan Wang, Minzhou Huang, Hanqing Chen, Ziyi Huang, Kaijie Zhang, Liyan Miao, Xueguang Zhang

Engineering 2023, Volume 30, Issue 11, Pages 190-202 doi: 10.1016/j.eng.2023.05.011

Abstract:

B7 homolog 3 (B7-H3) has attracted much attention in glioblastoma (GBM) radioimmunotherapy (RIT) duerecognize membrane expression of B7-H3 by human glioma cells.125sup>I labelling of the antibodies for single-photon emission computed tomography (SPECT) imagingThe biodistribution results of 125sup>I-SPECT imaging were similar to those of 89sup>Zr-PETThe PD analysis results indicated that 131I-hu4G4 had an excellent therapeutic effect and high safety

Keywords： B7-H3 Radioimmunotherapy Glioblastoma Pharmacokinetics Pharmacodynamics

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♮-convexity and its applications in operations

Xin CHEN

Frontiers of Engineering Management 2017, Volume 4, Issue 3, Pages 283-294 doi: 10.15302/J-FEM-2017057

Abstract: -convexity, one of the central concepts in discrete convex analysis, receives significant attentions in the operations literature in recent years as it provides a powerful tool to derive structures of optimal policies and allows for efficient computational procedures. In this paper, we present a survey of key properties of -convexity and some closely related results in lattice programming, several of which were developed recently and motivated by operations applications. As a new contribution to the literature, we establish the relationship between a notion called -differential monotonicity and -convexity. We then illustrate the techniques of applying -convexity through a detailed analysis of a perishable inventory model and a joint inventory and transshipment control model with random capacities.

Keywords： Li>&natur sup>-convexity lattice programming perishable inventory models random capacity

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Pentazolate Anion Cycloi>-N₅–sup>: Development of a New Energetic Material

Qiuhan Lin, Pengcheng Wang, Yuangang Xu, Ming Lu

Engineering 2020, Volume 6, Issue 9, Pages 964-966 doi: 10.1016/j.eng.2020.04.011

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Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in

Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 808-814 doi: 10.1007/s11684-021-0878-x

Abstract: Chinese families with EB, and eight variants including a novel nonsense variant (c.47G>A, p.W16*) in LAMA3i>, a known recurrent variant (c.74C>T, p.P25L) in KRT5i>, 2 novel (c.2531T>A, p.V844E; cCOL7A1 i>were detected.Notably, this study identified a nonsense variant in LAMA3i> that causes EB within the Chinese populationand revealed that this variant resulted in a reduction in LAMA3i> mRNA and protein expression levels

Keywords： epidermolysis bullosa LAMA3i> COL7A1i> KRT5i> Chinese families

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PtHAK5, a candidate for mediating high-affinity K

Haili YANG, Weidan ZHANG, Weiwei CHAI, Wenying WANG, Li GAO, Jing ZHANG, Yongping WANG, Suo-Min WANG

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 1, Pages 108-117 doi: 10.15302/J-FASE-2018200

Abstract: is a typical salt-exclu-ding halophytic grass with strong salt-tolerance, which enhances tolerance by restricting Na influx as well as having a strong selectivity for K over Na . The HAK5 K transporters generally modulate effective K acquisition in plants, especially under low K condition. In this study, from was isolated by RT-PCR and characterized using yeast complementation. The results showed PtHAK5 consisted of 784 amino acids and shared over 80% homology with the identified high-affinity K transporter HAK5 from other higher plants. The expression of rescued the K -uptake-defective phenotype of yeast strain CY162. In conclusion, PtHAK5 is a candidate for mediating high-affinity K uptake under low K conditions.

Keywords： K+sup> uptake PtHAK5 Puccinellia tenuiflorai> yeast complementation

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Transmission of Carbapenem Resistance Between Human and Animal NDM-Positive Escherichia colii> Strains Article

Yingbo Shen, Fupin Hu, Yongqiang Wang, Dandan Yin, Lu Yang, Yiqiang Chen, Chunyan Xu, Jiyun Li, Junyao Jiang, Xueyang Wang, Yulin Fu, Dongyan Shao, Dejun Liu, Tengfei Ma, Chang Cai, Zhangqi Shen, Shaolin Wang, Juan Li, Rong Zhang, Yuebin Ke, Congming Wu, Jianzhong Shen, Timothy R. Walsh, Yang Wang

Engineering 2022, Volume 15, Issue 8, Pages 24-33 doi: 10.1016/j.eng.2021.07.030

Abstract: 62.2% (n = 28/45) of chicken farms had a bla_NDM abundance of 1×10－5sup> to 1×10－3sup> and 1×10－3 to 1×10－2sup>, respectively.

Keywords： Carbapenem resistance i>Escherichia colii> blai>NDM-5sup> One Health Antimicrobial

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On the monolayer dispersion behavior of Co₃O₄ on HZSM-5 support: designing applicable catalysts for selective catalytic reduction of nitrogen oxides by ammonia

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11, Pages 1741-1754 doi: 10.1007/s11705-023-2332-x

Abstract: spontaneously disperse on HZSM-5 support with a monolayer dispersion threshold of 0.061 mmol 100 m–2sup>, equaling to a weight percentage around 4.5%.It has been revealed that the quantities of surface active oxygen (O₂–sup>) and acidsites are crucial for the reaction, which can adsorb and activate NO_xi> and NH_{3catalyst close to the monolayer dispersion capacity, possesses the most abundant active O₂<sup}

Keywords： Co₃O₄/ZSM-5 NO_xi>-SCR by NH₃ monolayer dispersionthreshold effect surface acid sites surface active O₂–sup> anions

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Anefficient data layout scheme for better I/O balancing inRAID-6 storage systems

Ping XIE,Jian-zhong HUANG,Er-wei DAI,Qiang CAO,Chang-sheng XIE

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 5, Pages 335-345 doi: 10.1631/FITEE.1400362

Abstract: Among redundant arrays of independent disks (RAID)-6 codes, maximum distance separable (MDS) based RAID-6 codes are popular because they have the optimal storage efficiency.vertical MDS codes exhibit better load balancing compared to horizontal MDS codes in partial stripes, an I/Os among P-coded disk arrays (i.e., PC).particular, in the case of a 12-disk array, the UPC scheme can improve the access performance of the RAID-6

Keywords： RAID-6 Data availability High performance I/O balancing

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RNA m6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

Ni>6sup>-methyladenosine (m6sup>A) is the most common post-transcriptional RNAsup>A modification could be installed by m6sup>A “writers” composed of core catalyticThe function of m6sup>A is executed by m6sup>A “readers” that bind to m6sup>A in different cells under normal or disease conditions.relevance and importance of m6sup>A modification in in vitroi> cell lines, in

Keywords： RNA modification m6sup>A immunity cancer epigenetics

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Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 4, Pages 448-455 doi: 10.1007/s11709-014-0262-x

Abstract: Rock mass classification system is very suitable for various engineering design and stability analysis. classification method is confirmed by Japan Highway Public Corporation that this method can figure out either strength or deformability of rock mass, further appropriating the amount of rock bolts, thickness of shotcrete, and size of pitch of steel ribs just after the blasting procedure. Based on these advantages of method, in this study, according to data of five deep and long tunnels in Iran, two equations for estimating the value of method from and classification systems were developed. These equations as a new method were able to optimize the support system for and classification systems. From classification and its application in these case studies, it is pointed out that the method for the design of support systems in underground working is more reliable than the and classification systems.

Keywords： JHi> classification Qi> and RMRi> classification new method

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The Potential Role of Powdery Mildew-Resistance Gene Pm40i> in Chinese Wheat-Breeding Programs inthe Post-Pm21i> Era Perspective

Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo

Engineering 2018, Volume 4, Issue 4, Pages 500-506 doi: 10.1016/j.eng.2018.06.004

Abstract: transferred into wheat in the 1980s, by translocating the Heuchera villosa chromosome arm 6VSto the wheat chromosome arm 6AL (6VS·6AL).Pm40 was identified and mapped on the wheat chromosome arm 7BS from several wheat lines developed

Keywords： Wheat Powdery mildew Pm21i> Pm40i> Alien species Native resistance

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NiFeRuO_xi> nanosheets on Ni foam as an electrocatalyst for efficient

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11, Pages 1698-1706 doi: 10.1007/s11705-023-2334-8

Abstract: The electrocatalyst NiFeRuO_xi>/NF, comprised of NiFeRuO_xi> nanosheetsNiFeRuO_xi>/NF displays high electrocatalytic activity and stability for overall alkalineseawater splitting: 98 mV@ 10 mA∙cm−2sup> in hydrogen evolution reaction, 318 mV@ 50 mA∙cm−2sup> in oxygen evolution reaction, and a cell voltage of 1.53 V@ 10 mA∙cm−2sup>, as wellA solar-driven system containing such a bifunctional NiFeRuO_xi>/NF has an almost 100%

Keywords： NiFeRuO_xi> nanosheets Ni foam electrocatalysis overall seawater splitting solar-driven

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Morphology selective construction of

Maher Darwish, Ali Mohammadi, Navid Assi, Samer Abuzerr, Youssef Alahmad

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 4, Pages 561-578 doi: 10.1007/s11705-019-1808-1

Abstract: Controlled growth of Bi WO nanorods with exposed [0 0 1] facets and the fabrication of an Fe O -Bi WO magnetic composite by a microwave-assisted polyol process, were achieved in this study. The adsorptivity and photocatalytic performance of the composite toward sunset yellow dye degradation were greatly enhanced by the -cyclodextrin cavities on its surface, firmly anchored through a cetyltrimethylammonium bromide linkage. A series of examinations and characterizations were carried out to determine the influence of various factors on the morphological modulation-photocatalytic behavior of the pure Bi WO prior to final functionalization. Changing the pH of the precursor solution impacted the formation of 0D, 2D, and 3D structures; however, the presence of hexamethylenetetramine surfactant induced the development of 1D nanorod structure. A reasonable crystal growth mechanism was proposed to elucidate the formation process. Conversely, the mechanism of the activity enhancement of -cyclodextrin functionalized Fe O -Bi WO , compared to that of the non-functionalized samples, could be realized with the assistance of chemical trapping experiments on sunset yellow, and was confirmed on the colorless antibiotic (sulfamethoxazole). The high performance and durability of this composite can be attributed to the facet-dependent activity, large adsorption capacity due to inclusion interactions, enhanced visible light absorption, and efficient charge separation.

Keywords： βi>-cyclodextrin Bi₂WO₆ shape controlled nanorod sunset yellow

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Title Author Date Type Operation

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

K+sup> and Na+sup> fluxes in roots of two Chinese Iris populations

Pinfang LI,Biao ZHANG

Journal Article

Therapeutic Characterization of 131sup>I-Labeled Humanized Anti-B7-H3 Antibodies for Radioimmunotherapy

Fengqing Fu, Meng Zheng, Shandong Zhao, Yan Wang, Minzhou Huang, Hanqing Chen, Ziyi Huang, Kaijie Zhang, Liyan Miao, Xueguang Zhang

Journal Article

♮-convexity and its applications in operations

Xin CHEN

Journal Article

Pentazolate Anion Cycloi>-N₅–sup>: Development of a New Energetic Material

Qiuhan Lin, Pengcheng Wang, Yuangang Xu, Ming Lu

Journal Article

Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in

Journal Article

PtHAK5, a candidate for mediating high-affinity K

Haili YANG, Weidan ZHANG, Weiwei CHAI, Wenying WANG, Li GAO, Jing ZHANG, Yongping WANG, Suo-Min WANG

Journal Article

Transmission of Carbapenem Resistance Between Human and Animal NDM-Positive Escherichia colii> Strains

Journal Article

On the monolayer dispersion behavior of Co₃O₄ on HZSM-5 support: designing applicable catalysts for selective catalytic reduction of nitrogen oxides by ammonia

Journal Article

Anefficient data layout scheme for better I/O balancing inRAID-6 storage systems

Ping XIE,Jian-zhong HUANG,Er-wei DAI,Qiang CAO,Chang-sheng XIE

Journal Article

RNA m6sup>A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article

Development of a new method for RMR and Q classification method to optimize support system in tunneling

Asghar RAHMATI,Lohrasb FARAMARZI,Manouchehr SANEI

Journal Article

The Potential Role of Powdery Mildew-Resistance Gene Pm40i> in Chinese Wheat-Breeding Programs inthe Post-Pm21i> Era

Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo